Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | YWHAG | P61981 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30664595 | 0.83 | KDM4E (0.54) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL14875455 | 0.83 | KDM4E (0.54) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL27791208 | 0.82 | KDM4E (0.68) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL10261801 | 0.81 | HTT (0.68) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL28143334 | 0.81 | ALDH1A1 (0.79) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL31454335 | 0.79 | MAPT (0.56) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL422548 | 0.79 | MAPT (0.56) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL10293479 | 0.79 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL853123 | 0.78 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL265878 | 0.77 | NR1H2 (0.50) | ALDH1A1LMNAMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103626742-B | Bi-aryl meta-pyrimidine inhibitors of kinases | 塔格根公司 | 2017-04-26 | — | — | CN | disclosed |