Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28794361 | 0.85 | ALDH1A1 (0.49) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL14334861 | 0.84 | KDM4E (0.67) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL7432215 | 0.83 | KDM4E (0.97) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL28843901 | 0.82 | ALDH1A1 (0.52) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL31038267 | 0.81 | KDM4E (1.00) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL195575 | 0.81 | KDM4E (1.00) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL14334867 | 0.81 | KDM4E (0.66) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL7435442 | 0.79 | KDM4E (0.75) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL14633623 | 0.79 | NPC1 (0.75) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL103154 | 0.77 | KDM4E (0.67) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101578275-A | Anilinopiperazine derivatives and methods of use thereof | SCHERING CORP (US) | 2009-11-11 | — | — | CN | disclosed |