Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.48 |
| ▸ | PTGIR | P43119 | 1/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27597764 | 0.98 | TRPM8 (0.55) | TRPM8KDM4EHPGDKMT2ATSHR | |
| SCHEMBL3470955 | 0.93 | CA1 (0.55) | TRPM8CES2CES1CA1CA2 | |
| SCHEMBL27515960 | 0.86 | ESR2 (0.52) | KMT2AMEN1CES2CES1CA1 | |
| SCHEMBL22204353 | 0.85 | TRPM8 (0.59) | TRPM8KDM4EHPGDKMT2ATSHR | |
| SCHEMBL7616834 | 0.84 | LMNA (0.50) | TRPM8KDM4EHPGDKMT2ATSHR | |
| SCHEMBL31393785 | 0.84 | KMT2A (0.66) | TRPM8KDM4EHPGDKMT2ATSHR | |
| SCHEMBL5852226 | 0.83 | ELANE (0.54) | KDM4EKMT2ATSHRMEN1NPC1 | |
| Methyl Alcohol SCHEMBL28147253 | 0.82 | NPSR1 (0.58) | TRPM8HPGDKMT2ATSHRMEN1 | |
| SCHEMBL75883 | 0.82 | NPSR1 (0.64) | TRPM8HPGDKMT2ATSHRMEN1 | |
| SCHEMBL75885 | 0.82 | NPSR1 (0.64) | TRPM8HPGDKMT2ATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104744356-B | The synthetic method of 2-substituted carbamide class compound | 上海大学 | 2017-05-31 | — | — | CN | disclosed |