Formic Acid

Formic Acid

SCHEMBL28844167

Clc1ccc(Cl)nc1.O=CO

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 1/20 0.47
KCNQ3 O43525 1/20 0.44
KCNQ2 O43526 1/20 0.44
KCNE1 P15382 1/20 0.44
KCNQ1 P51787 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
PTK2 Q05397 1/20 0.41
EGFR P00533 1/20 0.40
ADRA2A P08913 4/20 0.39
ADRA2B P18089 4/20 0.39
ADRA2C P18825 4/20 0.39
PLAU P00749 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
OXTR P30559 1/20 0.38
AVPR1A P37288 1/20 0.38
NFE2L2 Q16236 1/20 0.38
ALDH1A1 P00352 1/20 0.38
FDPS P14324 1/20 0.38
FDFT1 P37268 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL28190349 0.98 NAPRT (0.45) NAPRTKCNQ3KCNQ2KCNE1KCNQ1
SCHEMBL28048004 0.91 NAPRT (0.45) NAPRTKCNQ3KCNQ2KCNE1KCNQ1
SCHEMBL29538085 0.85
SCHEMBL17800 0.85
Formic Acid SCHEMBL28190351 0.84 SMN1; SMN2 (0.42) NAPRTKCNQ3KCNQ2KCNE1KCNQ1
SCHEMBL32681750 0.83
Ammonia Solution, Strong SCHEMBL14636438 0.83
Boric Acid SCHEMBL28809555 0.81 NAPRT (0.45) NAPRTKCNQ3KCNQ2KCNE1KCNQ1
Formic Acid SCHEMBL28841050 0.78 RAB9A (0.47) NAPRTKCNQ3KCNQ2ADRA2AADRA2B
Formic Acid SCHEMBL27823119 0.78 ALDH1A1 (0.44) NAPRTL3MBTL1EGFRADRA2AADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105801474-B A kind of method of refined 3,6 lontrel 张玲 2018-01-16 CN claimed
CN-104447529-B Method for extracting and purifying 3,6-matrigon 利尔化学股份有限公司 2017-05-24 CN claimed