Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17628989 | 0.79 | RORC (0.59) | RORC | |
| Hydrochloric Acid SCHEMBL17628917 | 0.78 | RORC (0.59) | RORC | |
| SCHEMBL17628768 | 0.77 | RORC (0.46) | RORC | |
| SCHEMBL22678034 | 0.75 | SRC (0.41) | — | |
| SCHEMBL17628850 | 0.71 | RORC (0.48) | RORC | |
| SCHEMBL17628779 | 0.71 | RORC (0.48) | RORC | |
| SCHEMBL24330155 | 0.69 | APP (0.46) | RORC | |
| Hydrochloric Acid SCHEMBL26911902 | 0.69 | APP (0.46) | RORC | |
| SCHEMBL17628965 | 0.68 | RORC (0.48) | RORC | |
| SCHEMBL17633420 | 0.68 | RORC (0.48) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715416-B | The pyrrolopyridine regulator and its application method that the methyl and trifluoromethyl of RORC2 replaces | 辉瑞大药厂 | 2019-07-23 | — | — | CN | disclosed |
| CN-106715416-A | Methyl-and trifluoromethyl-substituted pyrrolopyridine modulators of RORC2 and methods of use thereof | 辉瑞大药厂 | 2017-05-24 | — | — | CN | disclosed |