Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 15/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | TACR2 | P21452 | 1/20 | 0.57 |
| ▸ | DHODH | Q02127 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29864839 | 1.00 | TACR3 (0.65) | TACR3CYP3A4TACR2DHODHMEN1 | |
| SCHEMBL16098313 | 0.81 | TACR3 (0.73) | TACR3CYP3A4TACR2DHODH | |
| SCHEMBL3963611 | 0.79 | TACR3 (1.00) | TACR3CYP3A4TACR2DHODH | |
| SCHEMBL9199891 | 0.79 | LMNA (0.60) | CYP3A4MEN1KMT2AGAAADORA3 | |
| SCHEMBL3959255 | 0.78 | TACR3 (0.68) | TACR3CYP3A4TACR2DHODHLMNA | |
| SCHEMBL3961862 | 0.76 | TACR3 (0.67) | TACR3CYP3A4TACR2DHODHLMNA | |
| SCHEMBL8271391 | 0.76 | TACR3 (0.65) | TACR3CYP3A4TACR2DHODHLMNA | |
| Ethane SCHEMBL6100955 | 0.74 | TACR3 (0.54) | TACR3CYP3A4TACR2MEN1KMT2A | |
| SCHEMBL3959275 | 0.73 | TACR3 (1.00) | TACR3CYP3A4 | |
| SCHEMBL4895679 | 0.73 | TACR3 (1.00) | TACR3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110105279-B | Quinoline STAT3 specific inhibitor and preparation method and application thereof | 中山大学 | 2022-09-16 | — | — | CN | disclosed |