Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192241 | 0.87 | CYP3A4 (0.58) | LMNACYP3A4MEN1KMT2AGAA | |
| SCHEMBL28844477 | 0.79 | TACR3 (0.65) | LMNACYP3A4MEN1KMT2AGAA | |
| SCHEMBL29864839 | 0.79 | TACR3 (0.65) | LMNACYP3A4MEN1KMT2AGAA | |
| SCHEMBL11083265 | 0.76 | ADORA3 (0.63) | CYP3A4MEN1KMT2AGAAADORA3 | |
| SCHEMBL9197678 | 0.75 | CYP3A4 (0.57) | CYP3A4MEN1KMT2AGAAADORA3 | |
| SCHEMBL10388269 | 0.74 | ADORA3 (0.58) | LMNACYP3A4MEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL7451949 | 0.74 | DHODH (0.62) | LMNACYP3A4MEN1KMT2AGAA | |
| SCHEMBL7451940 | 0.74 | DHODH (0.56) | LMNACYP3A4MEN1KMT2AGAA | |
| SCHEMBL14148658 | 0.71 | LMNA (0.76) | LMNAMEN1KMT2AGAAPOLB | |
| SCHEMBL12189553 | 0.71 | NPC1 (0.57) | LMNACYP3A4MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292990-B1 | 4-Halopyridine-3-carboxamide compounds and herbicidal composition thereof | DAICEL CHEM (JP) | 1995-02-01 | — | — | EP | disclosed |
| US-4978385-A | 4-halopyridine-3-carboxamide compounds and herbicidal compositions thereof | DAICEL CHEMICAL INDUSTRIES LTD. (JP) | 1990-12-18 | — | — | US | disclosed |
| EP-0292990-A1 | 4-Halopyridine-3-carboxamide compounds and herbicidal composition thereof | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |