Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 4/20 | 0.63 |
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | UBE2I | P63279 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28953312 | 0.92 | TACR3 (0.76) | TACR3DHODHHDAC1KDM4EMEN1 | |
| SCHEMBL28844496 | 0.87 | TACR3 (0.61) | TACR3DHODHKDM4EMEN1KMT2A | |
| SCHEMBL28307588 | 0.86 | TACR3 (0.61) | TACR3DHODHHDAC1KDM4EMEN1 | |
| SCHEMBL28844498 | 0.78 | TACR3 (0.75) | TACR3DHODHMEN1KMT2AMAPT | |
| SCHEMBL6450481 | 0.78 | TACR3 (1.00) | TACR3HDAC1MEN1KMT2AMAPT | |
| SCHEMBL28844494 | 0.77 | TACR3 (0.88) | TACR3HDAC1KDM4EMEN1KMT2A | |
| SCHEMBL13190511 | 0.76 | DGAT1 (0.63) | TACR3DHODHMEN1KMT2AMAPT | |
| SCHEMBL6451612 | 0.73 | TACR3 (0.81) | TACR3HDAC1MEN1KMT2AMAPT | |
| SCHEMBL6450086 | 0.73 | TACR3 (1.00) | TACR3HDAC1KDM4EMEN1KMT2A | |
| SCHEMBL6630664 | 0.73 | TACR3 (0.72) | TACR3KDM4EMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110105279-B | Quinoline STAT3 specific inhibitor and preparation method and application thereof | 中山大学 | 2022-09-16 | — | — | CN | disclosed |