Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | TDO2 | P48775 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28844677 | 0.86 | IDO1 (0.54) | IDO1TDO2PTGS2PTGS1 | |
| SCHEMBL1144707 | 0.83 | KDM4E (0.52) | PRKCZCDK1CCNB1IDO1TDO2 | |
| SCHEMBL5357191 | 0.80 | CDK1 (0.52) | CDK1CCNB1IDO1TDO2ALOX15 | |
| SCHEMBL4044128 | 0.78 | ALOX15 (0.50) | CDK1CCNB1IDO1TDO2ALOX15 | |
| SCHEMBL3276933 | 0.75 | ALOX15 (0.47) | CDK1CCNB1IDO1TDO2ALOX15 | |
| SCHEMBL29865051 | 0.73 | IDO1 (0.77) | IDO1TDO2MAPTALDH1A1KMT2A | |
| SCHEMBL28471014 | 0.73 | IDO1 (0.77) | IDO1TDO2MAPTALDH1A1KMT2A | |
| SCHEMBL28455876 | 0.73 | ALOX15 (0.45) | CDK1CCNB1IDO1TDO2ALOX15 | |
| SCHEMBL28844731 | 0.73 | ALOX15 (0.45) | CDK1CCNB1IDO1TDO2ALOX15 | |
| SCHEMBL5737160 | 0.73 | KDM4E (0.51) | CDK1CCNB1GAAMAPTTUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483366-B | Indole compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-09-16 | — | — | CN | disclosed |