Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29732914 | 1.00 | IRAK4 (0.63) | IRAK4MEN1KMT2AMAPTGAA | |
| SCHEMBL29684506 | 0.87 | IRAK4 (0.57) | IRAK4MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL28844848 | 0.85 | HTT (0.70) | IRAK4MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL29732956 | 0.85 | HTT (0.70) | IRAK4MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL29684515 | 0.84 | IRAK4 (0.57) | IRAK4MEN1KMT2AMAPTGRM4 | |
| SCHEMBL29684150 | 0.83 | IRAK4 (0.53) | IRAK4MEN1KMT2AMAPTGRM4 | |
| SCHEMBL29684502 | 0.81 | IRAK4 (0.56) | IRAK4MEN1KMT2AMAPTGAA | |
| SCHEMBL29684405 | 0.80 | IRAK4 (0.55) | IRAK4MEN1KMT2AGRM4KDM4E | |
| SCHEMBL28844846 | 0.80 | LMNA (0.59) | IRAK4MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL359168 | 0.78 | IRAK4 (1.00) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114763347-B | Compound for inducing mesenchymal stem cells to differentiate into cartilage and application thereof | 华东师范大学 | 2024-06-21 | — | — | CN | claimed |
| CN-114763347-A | Compound for inducing mesenchymal stem cells to differentiate towards cartilage and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | claimed |
| CN-114763347-B | Compound for inducing mesenchymal stem cells to differentiate into cartilage and application thereof | 华东师范大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-114763347-A | Compound for inducing mesenchymal stem cells to differentiate towards cartilage and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | disclosed |