Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.57 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29732956 | 1.00 | HTT (0.70) | HTTKMT2AKDM4EIRAK4KCNMA1 | |
| SCHEMBL10889701 | 0.85 | MAPK1 (0.72) | KMT2AKDM4EKCNMA1ALDH1A1L3MBTL1 | |
| SCHEMBL29732914 | 0.85 | IRAK4 (0.63) | HTTKMT2AKDM4EIRAK4ALDH1A1 | |
| SCHEMBL28844843 | 0.85 | IRAK4 (0.63) | HTTKMT2AKDM4EIRAK4ALDH1A1 | |
| SCHEMBL29732903 | 0.84 | LMNA (0.59) | HTTKMT2AIRAK4ALDH1A1L3MBTL1 | |
| SCHEMBL28844846 | 0.84 | LMNA (0.59) | HTTKMT2AIRAK4ALDH1A1L3MBTL1 | |
| SCHEMBL29684423 | 0.83 | KCNMA1 (0.60) | HTTKMT2AKDM4EIRAK4KCNMA1 | |
| SCHEMBL29732921 | 0.82 | SMN1; SMN2 (0.77) | KMT2AKDM4EIRAK4ALDH1A1HPGD | |
| SCHEMBL28844943 | 0.82 | SMN1; SMN2 (0.77) | KMT2AKDM4EIRAK4ALDH1A1HPGD | |
| SCHEMBL29732897 | 0.81 | KCNMA1 (0.60) | HTTKMT2AKDM4EIRAK4KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114763347-A | Compound for inducing mesenchymal stem cells to differentiate towards cartilage and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | claimed |
| CN-114763347-B | Compound for inducing mesenchymal stem cells to differentiate into cartilage and application thereof | 华东师范大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-114763347-A | Compound for inducing mesenchymal stem cells to differentiate towards cartilage and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | disclosed |