Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.52 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.52 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29732813 | 1.00 | NPC1 (0.64) | NPC1HPGDALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL18906063 | 0.84 | HPGD (0.59) | NPC1HPGDALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL13895327 | 0.83 | HPGD (0.59) | NPC1HPGDALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL29684591 | 0.82 | NPC1 (0.59) | NPC1HPGDALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL2925459 | 0.82 | NPC1 (0.71) | NPC1HPGDALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL29732908 | 0.80 | HPGD (0.54) | NPC1HPGDALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL12993479 | 0.80 | TSHR (0.56) | NPC1HPGDALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL28844940 | 0.80 | HPGD (0.54) | NPC1HPGDALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL6123167 | 0.80 | ALDH1A1 (0.74) | NPC1HPGDALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL9365875 | 0.79 | ACKR3 (0.64) | NPC1HPGDALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114763347-A | Compound for inducing mesenchymal stem cells to differentiate towards cartilage and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | claimed |
| CN-114763347-B | Compound for inducing mesenchymal stem cells to differentiate into cartilage and application thereof | 华东师范大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-114763347-A | Compound for inducing mesenchymal stem cells to differentiate towards cartilage and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | disclosed |