Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.53 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.53 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.51 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29732908 | 1.00 | HPGD (0.54) | HPGDSENP5SENP2SENP1ALDH1A1 | |
| SCHEMBL28844939 | 0.85 | HPGD (0.63) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18906063 | 0.81 | HPGD (0.59) | HPGDSENP5SENP2SENP1ALDH1A1 | |
| SCHEMBL13895327 | 0.80 | HPGD (0.59) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28844872 | 0.80 | NPC1 (0.64) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29732813 | 0.80 | NPC1 (0.64) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29684591 | 0.78 | NPC1 (0.59) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2925459 | 0.78 | NPC1 (0.71) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9365904 | 0.78 | MAOA (0.66) | ERCC1ERCC4MAOAROCK2 | |
| SCHEMBL3461756 | 0.77 | ERCC1 (0.60) | ERCC1ERCC4SMN1; SMN2TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114763347-A | Compound for inducing mesenchymal stem cells to differentiate towards cartilage and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | claimed |
| CN-114763347-B | Compound for inducing mesenchymal stem cells to differentiate into cartilage and application thereof | 华东师范大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-114763347-A | Compound for inducing mesenchymal stem cells to differentiate towards cartilage and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | disclosed |