Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29732923 | 1.00 | KMT2A (0.55) | KMT2AALDH1A1MEN1GAALMNA | |
| SCHEMBL28844870 | 0.89 | BACE1 (0.56) | KMT2AALDH1A1MEN1GAALMNA | |
| SCHEMBL29733128 | 0.89 | BACE1 (0.56) | KMT2AALDH1A1MEN1GAALMNA | |
| SCHEMBL28844846 | 0.84 | LMNA (0.59) | KMT2AALDH1A1MEN1LMNAIRAK4 | |
| SCHEMBL29732903 | 0.84 | LMNA (0.59) | KMT2AALDH1A1MEN1LMNAIRAK4 | |
| SCHEMBL28844945 | 0.82 | KMT2A (0.52) | KMT2AALDH1A1MEN1LMNAKDM4E | |
| SCHEMBL29732762 | 0.82 | KMT2A (0.52) | KMT2AALDH1A1MEN1LMNAKDM4E | |
| SCHEMBL29733013 | 0.82 | MEN1 (0.57) | KMT2AALDH1A1MEN1LMNAKDM4E | |
| SCHEMBL28844878 | 0.82 | MEN1 (0.57) | KMT2AALDH1A1MEN1LMNAKDM4E | |
| SCHEMBL29732958 | 0.81 | KCNQ2 (0.53) | KMT2AALDH1A1MEN1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114763347-B | Compound for inducing mesenchymal stem cells to differentiate into cartilage and application thereof | 华东师范大学 | 2024-06-21 | — | — | CN | claimed |
| CN-114763347-B | Compound for inducing mesenchymal stem cells to differentiate into cartilage and application thereof | 华东师范大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-114763347-A | Compound for inducing mesenchymal stem cells to differentiate towards cartilage and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | disclosed |