Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BPTF | Q12830 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28148039 | 0.78 | CYP3A4 (0.40) | LMNACYP2C9 | |
| SCHEMBL28148038 | 0.73 | CYP3A4 (0.42) | HSD11B1L3MBTL1LMNATHRBCYP2C9 | |
| SCHEMBL1404045 | 0.68 | HSD11B1 (0.30) | HSD11B1L3MBTL1 | |
| SCHEMBL277859 | 0.67 | HTT (0.32) | HSD11B1L3MBTL1THRBCYP2C9 | |
| SCHEMBL16054051 | 0.67 | EPHX1 (0.33) | HSD11B1L3MBTL1 | |
| SCHEMBL3390481 | 0.63 | — | — | |
| SCHEMBL493467 | 0.63 | HTT (0.36) | HSD11B1L3MBTL1MEN1KMT2A | |
| SCHEMBL18921038 | 0.62 | HSD11B1 (0.35) | HSD11B1L3MBTL1THRBCYP2C9 | |
| SCHEMBL21391723 | 0.62 | — | — | |
| SCHEMBL4961193 | 0.62 | LMNA (0.35) | SMN1; SMN2LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115368440-A | Euphausia superba oligomeric composite peptide | 山东鲁华海洋生物科技有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-106928126-A | A kind of amide derivatives and preparation method thereof and application pharmaceutically | 四川海思科制药有限公司 | 2017-07-07 | — | — | CN | disclosed |
| CN-106699744-A | Heterocyclic acylamide derivative and preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2017-05-24 | — | — | CN | disclosed |