Toluene

Toluene

SCHEMBL28845148

CC(CO)CO.Cc1ccccc1

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.55
TSHR P16473 3/20 0.55
ALOX12 P18054 1/20 0.55
ACHE P22303 1/20 0.55
TRPA1 O75762 6/20 0.54
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
KMT2A Q03164 1/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
KAT2B Q92831 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
HPGD P15428 1/20 0.36
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.35
MAOA P21397 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL9064228 0.89 TRPA1 (0.48) LMNATSHRALOX12ACHETRPA1
Toluene SCHEMBL744674 0.87 TSHR (0.58) LMNATSHRALOX12ACHETRPA1
Toluene SCHEMBL28909233 0.85 TSHR (0.55) LMNATSHRALOX12ACHETRPA1
Toluene SCHEMBL27977612 0.85 TSHR (0.55) LMNATSHRALOX12ACHETRPA1
Toluene SCHEMBL11299292 0.85 LMNA (0.55) LMNATSHRALOX12ACHETRPA1
Toluene SCHEMBL11300923 0.83 TSHR (0.52) LMNATSHRALOX12ACHETRPA1
Toluene SCHEMBL11480026 0.81 LMNA (0.50) LMNATSHRALOX12ACHETRPA1
Toluene SCHEMBL11482275 0.81 LMNA (0.50) LMNATSHRALOX12ACHETRPA1
Benzene SCHEMBL11434321 0.81 TRPA1 (0.50) TSHRTRPA1KAT2B
Toluene SCHEMBL11058611 0.80 LMNA (0.55) LMNATSHRALOX12ACHETRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104603171-B Carbon monoxide-olefin polymeric and the manufacture method using its polyurethane resin for manufacturing polyurethane resin 东曹株式会社 2017-05-31 CN disclosed