Fluoride

Fluoride

SCHEMBL28845398

CC(C)Cl.COC(C)(C)C.F

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.61
TSHR P16473 3/20 0.36
TDP1 Q9NUW8 2/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15156484 0.92 ALDH1A1 (0.61) ALDH1A1TSHRTDP1MAPK1
Chloroform SCHEMBL1750330 0.88 ALDH1A1 (0.67) ALDH1A1TSHRTDP1
Chloromethane SCHEMBL774036 0.83
Fluoride SCHEMBL28153471 0.81 ALDH1A1 (0.57) ALDH1A1
Fluoride SCHEMBL2684369 0.79 ALDH1A1 (0.80) ALDH1A1TSHRTDP1
Fluoride SCHEMBL15135042 0.79 ALDH1A1 (0.80) ALDH1A1TSHRTDP1
SCHEMBL503396 0.78
SCHEMBL8679785 0.78 ALDH1A1 (1.00) ALDH1A1TSHRTDP1
SCHEMBL6223 0.78
Isopropyl Alcohol SCHEMBL457362 0.77 ALDH1A1 (0.61) ALDH1A1TSHRTDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106748807-A A kind of sevoflurane isopropyl amine preparation method of 2 methyl of high-purity 4 衢州学院 2017-05-31 CN disclosed