Chloroform

Chloroform

SCHEMBL1750330

COC(C)(C)C.ClC(Cl)Cl

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.67
TSHR P16473 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL28845398 0.88 ALDH1A1 (0.61) ALDH1A1TSHRTDP1
SCHEMBL15156484 0.88 ALDH1A1 (0.61) ALDH1A1TSHRTDP1
Chloromethane SCHEMBL774036 0.87
SCHEMBL503396 0.82
SCHEMBL6223 0.82
SCHEMBL8679785 0.82 ALDH1A1 (1.00) ALDH1A1TSHRTDP1
Water SCHEMBL10335432 0.77
SCHEMBL3662439 0.77
SCHEMBL3664027 0.77
SCHEMBL3366971 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899744-B2 Crystalline form of compound suppressing protein kinase activity, and application thereof XCOVERY HOLDINGS, INC. (US) 2021-01-26 US claimed
US-20190135792-A1 CRYSTALLINE FORM OF COMPOUND SUPPRESSING PROTEIN KINASE ACTIVITY, AND APPLICATION THEREOF XCOVERY HOLDINGS, INC. 2019-05-09 US claimed
EP-3470410-A1 CRYSTALLINE FORM OF COMPOUND SUPPRESSING PROTEIN KINASE ACTIVITY, AND APPLICATION THEREOF XCOVERY Holding Company, LLC (CN) 2019-04-17 EP claimed
WO-2008117282-A1 POLYMORPH OF GRANISETRON BASE AND PRODUCTION PROCESS THEREFOR CHEMAGIS LTD. (IL) 2008-10-02 WO claimed
US-20080242696-A1 CRYSTALLINE GRANISETRON BASE AND PRODUCTION PROCESS THEREFOR CHEMAGIS LTD. (IL) 2008-10-02 US claimed
EP-4400498-A1 AMORPHOUS SUBSTANCES, CRYSTALS, PHARMACEUTICAL COMPOSITIONS, PREPARATION METHODS AND USES OF THIOHYDANTOIN COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF Suzhou Kintor Pharmaceuticals, Inc. (CN) 2024-07-17 EP disclosed
US-20240182442-A1 ANHYDROUS POLYMORPHS OF ANDROGEN RECEPTOR ANTAGONIST, PREPARATION METHOD THEREFOR, AND USE THEREOF SUZHOU KINTOR PHARMACEUTICALS, INC. (CN) 2024-06-06 US disclosed
CN-117736176-A Pharmaceutically acceptable salts of androgen receptor antagonists and polymorphs thereof, methods of preparation and use 苏州开拓药业股份有限公司 2024-03-22 CN disclosed
EP-4317136-A1 ANHYDROUS POLYMORPHS OF ANDROGEN RECEPTOR ANTAGONIST, PREPARATION METHOD THEREFOR, AND USE THEREOF Suzhou Kintor Pharmaceuticals, Inc. (CN) 2024-02-07 EP disclosed
CN-117043142-A Anhydrous polymorphs of androgen receptor antagonists, methods of making and uses thereof 苏州开拓药业股份有限公司 2023-11-10 CN disclosed
CN-116284089-A Fluoboric part cyanine fluorescent probe and preparation method and application thereof 四川大学华西医院 2023-06-23 CN disclosed
CN-109789146-B Chemokine receptor modulators and uses thereof 拉普特医疗公司 2023-04-18 CN disclosed
EP-0880540-B1 17-BETA-CYCLOPROPYL(AMINO/OXY) 4-AZA STEROIDS AS ACTIVE INHIBITORS OF TESTOSTERONE 5-ALPHA-REDUCTASE AND C17-20-LYASE AVENTIS PHARMA INC (US) 2002-06-12 EP disclosed
US-6365597-B1 FOR THERAPY OF ANDROGEN AND ESTROGEN MEDIATED DISORDERS, INCLUDING BENIGN PROSTATIC HYPERPLASIA, ANDROGEN MEDIATED PROSTATE CANCER, ESTROGEN MEDIATED BREAST CANCER AND ACNE AVENTIS PHARMACEUTICALS INC. 2002-04-02 US disclosed
US-5866589-A Alkyl substituted piperadinyl and piperazinyl anti-AIDS compounds PHARMACIA & UPJOHN COMPANY (US) 1999-02-02 US disclosed
US-5693663-A PESTICIDES; HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-02 US disclosed
EP-0797576-A1 ALKYL SUBSTITUTED PIPERADINYL AND PIPERAZINYL ANTI-AIDS COMPOUNDS PHARMACIA & UPJOHN COMPANY (US) 1997-10-01 EP disclosed
US-5585384-A 1-OXY-FUNCTIONAL GROUP-2-ALKYLARYL-3-OXO-PYRROLIZINES; INSECTICIDES; NEMATOCIDES; HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-12-17 US disclosed
WO-1996018628-A1 ALKYL SUBSTITUTED PIPERADINYL AND PIPERAZINYL ANTI-AIDS COMPOUNDS PHARMACIA & UPJOHN COMPANY (US) 1996-06-20 WO disclosed
US-5288874-A Insecticides, miticides BAYER AKTIENGESELLSCHAFT (DE) 1994-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080242696-A1 CRYSTALLINE GRANISETRON BASE AND PRODUCTION PROCESS THEREFOR GCG, CRH, GCGR ALDH1A1 4484/4885TSHR 1240/4885TDP1 762/4885
US-10899744-B2 Crystalline form of compound suppressing protein kinase activity, and application thereof MAPKAPK5, MAP3K6, MAP3K5 ALDH1A1 4112/4885TSHR 2309/4885TDP1 2260/4885
US-20240182442-A1 ANHYDROUS POLYMORPHS OF ANDROGEN RECEPTOR ANTAGONIST, PREPARATION METHOD THEREFOR, AND USE THEREOF AR, NR5A1, CYP19A1 ALDH1A1 392/4885TSHR 1913/4885TDP1 3647/4885
US-20190135792-A1 CRYSTALLINE FORM OF COMPOUND SUPPRESSING PROTEIN KINASE ACTIVITY, AND APPLICATION THEREOF MAPKAPK5, MAP3K6, MAP3K5 ALDH1A1 4112/4885TSHR 2309/4885TDP1 2260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.