Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768305 | 0.88 | MYC (0.41) | MYCDRD1HTR7CA12CA1 | |
| SCHEMBL28152682 | 0.88 | TDP1 (0.42) | DRD1CYP3A4TDP1PDCD1CD274 | |
| SCHEMBL1768199 | 0.86 | TDP1 (0.41) | DRD1CYP3A4TDP1PDCD1CD274 | |
| SCHEMBL13886510 | 0.82 | DRD1 (0.41) | MYCDRD1HTR7CYP3A4TDP1 | |
| SCHEMBL13886498 | 0.82 | ALDH1A1 (0.39) | MYCDRD1HTR7CA12CA1 | |
| SCHEMBL8437351 | 0.81 | MYC (0.41) | MYCDRD1HTR7CA12CA1 | |
| SCHEMBL14604150 | 0.81 | CYP3A4 (0.39) | DRD1HTR7CA12CA1CA2 | |
| SCHEMBL19664922 | 0.80 | TDP1 (0.42) | DRD1CYP3A4TDP1PDCD1CD274 | |
| SCHEMBL30142870 | 0.80 | TDP1 (0.46) | MYCDRD1CA1CA2CA9 | |
| SCHEMBL301645 | 0.80 | TDP1 (0.46) | MYCDRD1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106674279-B | Aryl substituted biphenyl, pyrroles, indoles or dinaphthalene type monophosphorus ligand preparation method | 南京大学 | 2018-06-05 | — | — | CN | disclosed |
| CN-106674279-A | Preparation method for aryl-substituted biphenyl, pyrrole, indol or binaphthyl monophosphine ligand | 南京大学 | 2017-05-17 | — | — | CN | disclosed |