Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.54 |
| ▸ | DNMT3A | Q9Y6K1 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29809959 | 1.00 | RXFP1 (0.55) | RXFP1DNMT1DNMT3AMAPTKMT2A | |
| SCHEMBL28845675 | 0.87 | DNMT1 (0.68) | RXFP1DNMT1DNMT3AMAPTLMNA | |
| SCHEMBL28845676 | 0.87 | RXFP1 (0.59) | RXFP1DNMT1NPC1RAB9A | |
| SCHEMBL29809944 | 0.87 | RXFP1 (0.59) | RXFP1DNMT1NPC1RAB9A | |
| SCHEMBL28845693 | 0.85 | MEN1 (0.61) | RXFP1DNMT1DNMT3AMAPTKMT2A | |
| SCHEMBL29809955 | 0.85 | MEN1 (0.61) | RXFP1DNMT1DNMT3AMAPTKMT2A | |
| SCHEMBL28845688 | 0.83 | DNMT1 (0.63) | RXFP1DNMT1DNMT3ALMNAAURKA | |
| SCHEMBL29200469 | 0.82 | GAK (0.55) | DNMT1DNMT3ANPC1AKR1C3AKR1C2 | |
| SCHEMBL13335917 | 0.81 | DNMT1 (0.69) | DNMT1DNMT3AMAPTKMT2AMEN1 | |
| SCHEMBL28845668 | 0.81 | GAA (0.60) | DNMT1DNMT3AMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773267-B | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2024-01-26 | — | — | CN | claimed |
| CN-114773267-A | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2022-07-22 | — | — | CN | claimed |
| CN-114773267-B | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-114773267-A | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2022-07-22 | — | — | CN | disclosed |