Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.57 |
| ▸ | DNMT3A | Q9Y6K1 | 3/20 | 0.57 |
| ▸ | BRAF | P15056 | 5/20 | 0.52 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.50 |
| ▸ | DNMT3L | Q9UJW3 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 2/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
| ▸ | GAK | O14976 | 2/20 | 0.48 |
| ▸ | GSK3A | P49840 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | MARK3 | P27448 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28845675 | 0.89 | DNMT1 (0.68) | DNMT1DNMT3AEHMT1DNMT3LMAPT | |
| SCHEMBL28845667 | 0.89 | KCNK3 (0.55) | GAADNMT1DNMT3ABRAFEHMT1 | |
| SCHEMBL29809955 | 0.88 | MEN1 (0.61) | DNMT1DNMT3ABRAFEHMT1DNMT3L | |
| SCHEMBL28845693 | 0.88 | MEN1 (0.61) | DNMT1DNMT3ABRAFEHMT1DNMT3L | |
| SCHEMBL28845678 | 0.84 | TAS2R14 (0.52) | GAADNMT1MAPTGAKGSK3A | |
| SCHEMBL29809961 | 0.84 | TAS2R14 (0.52) | GAADNMT1MAPTGAKGSK3A | |
| SCHEMBL29200469 | 0.84 | GAK (0.55) | DNMT1DNMT3AAURKAGAKGSK3A | |
| SCHEMBL28845688 | 0.84 | DNMT1 (0.63) | DNMT1DNMT3AEHMT1DNMT3LAURKA | |
| SCHEMBL28845637 | 0.83 | DNMT1 (0.52) | DNMT1DNMT3AEHMT1DNMT3LPOLB | |
| SCHEMBL28845648 | 0.83 | NPSR1 (0.56) | DNMT1DNMT3AEHMT1DNMT3LAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773267-A | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2022-07-22 | — | — | CN | claimed |
| CN-114773267-B | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-114773267-A | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2022-07-22 | — | — | CN | disclosed |