Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PHGDH | O43175 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29809901 | 1.00 | KMT2A (0.52) | KMT2AMEN1POLBSMN1; SMN2MAPKAPK2 | |
| SCHEMBL11731115 | 0.93 | RAD52 (0.54) | KMT2AMEN1POLBSMN1; SMN2MAPKAPK2 | |
| SCHEMBL11542231 | 0.89 | SLC6A7 (0.60) | MAPKAPK2SLC6A7TSHRALDH1A1L3MBTL1 | |
| SCHEMBL7346130 | 0.89 | PDGFRB (0.51) | MAPKAPK2SLC6A7PDGFRBNAMPT | |
| SCHEMBL28845655 | 0.89 | MAPKAPK2 (0.53) | KMT2AMEN1MAPKAPK2MAPTLMNA | |
| SCHEMBL28845646 | 0.89 | RAD52 (0.56) | KMT2AMEN1POLBSMN1; SMN2MAPKAPK2 | |
| SCHEMBL11543145 | 0.87 | GAK (0.49) | KMT2AMEN1SMN1; SMN2MAPKAPK2MAPT | |
| SCHEMBL11736021 | 0.87 | HPGD (0.52) | KMT2AMEN1POLBMAPKAPK2TSHR | |
| SCHEMBL11542636 | 0.87 | PDGFRB (0.53) | POLBMAPKAPK2MAPTALDH1A1NPSR1 | |
| SCHEMBL28845636 | 0.87 | DRD2 (0.51) | KMT2AMEN1POLBSMN1; SMN2MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773267-B | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2024-01-26 | — | — | CN | claimed |
| CN-114773267-A | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2022-07-22 | — | — | CN | claimed |
| CN-114773267-B | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-114773267-A | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2022-07-22 | — | — | CN | disclosed |