SCHEMBL28845752

SCHEMBL28845752

O=C1C=C(Br)C(=O)c2cc(Br)ccc21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 2/20 0.61
PTPRC P08575 2/20 0.53
BCL2 P10415 2/20 0.52
MCL1 Q07820 1/20 0.52
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA4 P22748 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
P4HB P07237 1/20 0.42
TGM2 P21980 1/20 0.41
CES1 P23141 1/20 0.41
TRPV1 Q8NER1 1/20 0.41
LCK P06239 1/20 0.40
METAP1 P53582 1/20 0.39
MAPK1 P28482 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CYP1A2 P05177 1/20 0.38
ESR1 P03372 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30978710 0.87 S100A4 (0.54) S100A4PTPRCBCL2MCL1CA1
Acridine SCHEMBL28153648 0.83 PTPRC (0.46) S100A4PTPRCBCL2MCL1P4HB
SCHEMBL18992188 0.80 BCL2 (0.58) S100A4PTPRCBCL2MCL1CA1
SCHEMBL8773094 0.79 PTPRC (0.61) S100A4PTPRCBCL2MCL1CA1
SCHEMBL39700 0.77 S100A4 (0.90) S100A4PTPRCBCL2MCL1CA1
SCHEMBL762135 0.77 S100A4 (0.80) S100A4PTPRCBCL2MCL1CA1
SCHEMBL29514452 0.77 S100A4 (1.00) S100A4PTPRCBCL2MCL1CA1
SCHEMBL29390614 0.77 S100A4 (0.90) S100A4PTPRCBCL2MCL1CA1
SCHEMBL29664078 0.77 S100A4 (0.80) S100A4PTPRCBCL2MCL1CA1
SCHEMBL3717374 0.77 S100A4 (0.80) S100A4PTPRCBCL2MCL1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106800533-B A kind of naphthoquinones class electroluminescent organic material and its preparation method and application 中节能万润股份有限公司 2019-06-28 CN disclosed
CN-106800533-A A kind of naphthoquinones class electroluminescent organic material and its preparation method and application 中节能万润股份有限公司 2017-06-06 CN disclosed