Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13606736 | 0.85 | TDP1 (0.48) | TDP1ALDH1A1SMN1; SMN2LMNACES2 | |
| SCHEMBL9659492 | 0.85 | CA1 (0.48) | TDP1ALDH1A1LMNACES2SRD5A2 | |
| SCHEMBL9659486 | 0.85 | CA1 (0.48) | TDP1ALDH1A1LMNACES2SRD5A2 | |
| SCHEMBL8007984 | 0.84 | TSHR (0.48) | ALDH1A1SMN1; SMN2LMNACES2CES1 | |
| SCHEMBL3958996 | 0.84 | TSHR (0.48) | ALDH1A1SMN1; SMN2LMNACES2CES1 | |
| SCHEMBL3689392 | 0.84 | TSHR (0.48) | ALDH1A1SMN1; SMN2LMNACES2CES1 | |
| SCHEMBL4457854 | 0.84 | MAOB (0.61) | ALDH1A1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL31264445 | 0.83 | CES2 (0.43) | SMN1; SMN2LMNACES2CES1MAPT | |
| SCHEMBL11471533 | 0.83 | CA1 (0.57) | ALDH1A1SMN1; SMN2LMNACES2CES1 | |
| SCHEMBL8022236 | 0.83 | POLB (0.49) | ALDH1A1SMN1; SMN2CES2CES1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773204-A | Method for continuously preparing benzyl bromide derivative | 浙江禾本科技股份有限公司 | 2022-07-22 | — | — | CN | disclosed |