Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 5/20 | 0.42 |
| ▸ | CES2 | O00748 | 4/20 | 0.42 |
| ▸ | TYMP | P19971 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3958996 | 1.00 | TSHR (0.48) | TSHRGAACYP2C19CES1CES2 | |
| SCHEMBL8007984 | 1.00 | TSHR (0.48) | TSHRGAACYP2C19CES1CES2 | |
| SCHEMBL2045476 | 0.87 | TSHR (0.44) | TSHRGAACYP2C19CES1CES2 | |
| SCHEMBL2045474 | 0.87 | TSHR (0.44) | TSHRGAACYP2C19CES1CES2 | |
| SCHEMBL9900446 | 0.86 | CES2 (0.50) | TSHRGAACYP2C19CES1CES2 | |
| SCHEMBL9900449 | 0.86 | CES2 (0.50) | TSHRGAACYP2C19CES1CES2 | |
| SCHEMBL3689389 | 0.86 | TSHR (0.47) | TSHRGAACYP2C19CES1CES2 | |
| SCHEMBL3689388 | 0.86 | TSHR (0.47) | TSHRGAACYP2C19CES1CES2 | |
| SCHEMBL7805644 | 0.86 | CES1 (0.48) | TSHRGAACYP2C19CES1CES2 | |
| SCHEMBL7651351 | 0.86 | CES1 (0.48) | TSHRGAACYP2C19CES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112851546-B | Preparation method of (E) -2-methyl-alpha-methoxyiminophenylacetic acid methyl ester and intermediate thereof | 江西天宇化工有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-1111536-C | Preparation method of 13-ester derivatives of milbemycins and intermediates thereof | SANKYO CO (JP) | 2003-06-18 | — | — | CN | claimed |
| CN-1310719-A | Process for producing 13-ester derivatives of milbemycins | SANKYO CO (JP) | 2001-08-29 | — | — | CN | claimed |
| CN-1046275-C | 2-methoxyiminophenyl-N-methylacetamide derivatives, process for their preparation, their use and compositions containing them | BASF AG (DE) | 1999-11-10 | — | — | CN | claimed |
| EP-0869963-A1 | ARTHROPODICIDAL AND FUNGICIDAL ORGANOSILANES AND ORGANOGERMANES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-10-14 | — | — | EP | claimed |
| WO-1996017851-A1 | ARTHROPODICIDAL AND FUNGICIDAL ORGANOSILANES AND ORGANOGERMANES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-06-13 | — | — | WO | claimed |
| CN-1118165-A | Ortho-substituted 2-methoxyiminophenylacetic acid methylamides | BASF AG (DE) | 1996-03-06 | — | — | CN | claimed |
| JP-7076564-A | — | — | None | — | — | JP | disclosed |
| CN-117185954-A | Preparation method of (E) -2-methyl-alpha-methoxyiminophenylacetic acid methyl ester and intermediate thereof | 江西天宇化工有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-112851546-B | Preparation method of (E) -2-methyl-alpha-methoxyiminophenylacetic acid methyl ester and intermediate thereof | 江西天宇化工有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-112661732-B | Furanol derivative and preparation method and application thereof | 湖南化研院检测技术有限公司 | 2023-08-04 | — | — | CN | disclosed |
| US-11647750-B2 | Active compound combinations having insecticidal/acaricidal properties | BAYER AKTIENGESELLSCHAFT (DE) | 2023-05-16 | — | — | US | disclosed |
| CN-111217828-B | Preparation method of lepistamycin and intermediate thereof | 浙江海正药业股份有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-1098089-A | The method for preparing 2-oximino acetogenin | BAYER AG (DE) | 1995-02-01 | — | — | CN | disclosed |
| EP-0600835-A1 | Method for the production of derivatives of phenylacetic acid esters | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |
| US-4490524-A | BACTERICIDES | TOYO JOZO KABUSHIKI KAISHA (JP) | 1984-12-25 | — | — | US | disclosed |
| US-4203896-A | WITH MERCURIC ACETATE AND ACETIC ACID, ACIDIC HYDROLYSIS OF N-PROPENYL GROUP | ELI LILLY AND COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4178443-A | Derivatives of 7 [-substituted oxyimins acetamido] cephalosporins | HOFFMANN-LA ROCHE INC. (US) | 1979-12-11 | — | — | US | disclosed |
| US-4144232-A | Substituted azetidin-2-one antibiotics | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |
| US-4138555-A | BACTERICIDES | GLAXO LABORATORIES, LIMITED (GB) | 1979-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11647750-B2 | Active compound combinations having insecticidal/acaricidal properties | ACHE, CYP51A1, ACAT1 | TSHR 4661/4885GAA 73/4885CYP2C19 1006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.