Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3322544 | 0.79 | TSHR (0.38) | DPP4F2TSHRHTR2ATAAR1 | |
| SCHEMBL13388150 | 0.77 | CYP2C19 (0.36) | DPP4F2TSHRHTR2ATAAR1 | |
| SCHEMBL16924879 | 0.76 | DPP4 (0.39) | DPP4F2TSHRHTR2ATAAR1 | |
| SCHEMBL20765676 | 0.74 | CYP2D6 (0.44) | DPP4F2TSHRCYP2D6SRC | |
| SCHEMBL3949902 | 0.74 | DPP4 (0.38) | DPP4F2TSHRHTR2ATAAR1 | |
| SCHEMBL874358 | 0.74 | CYP2D6 (0.44) | DPP4F2TSHRCYP2D6SRC | |
| SCHEMBL11782888 | 0.74 | DPP4 (0.38) | DPP4F2TSHRHTR2ATAAR1 | |
| SCHEMBL3245737 | 0.72 | CYP1A2 (0.36) | DPP4F2TSHRHTR2ATAAR1 | |
| SCHEMBL7793933 | 0.72 | CYP2D6 (0.37) | DPP4F2TSHRHTR2ATAAR1 | |
| SCHEMBL7621141 | 0.70 | MEN1 (0.37) | DPP4F2TSHRHTR2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104478735-B | The imaging of central nervous system disease, diagnosis and/or treatment compound | 皮拉马影像股份公司 | 2017-05-31 | — | — | CN | disclosed |