SCHEMBL3322544

SCHEMBL3322544

C=CC(F)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
DPP4 P27487 2/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP2C19 P33261 1/20 0.38
F2 P00734 1/20 0.38
CYP3A4 P08684 2/20 0.37
KDM4E B2RXH2 2/20 0.37
MAPT P10636 2/20 0.37
ALOX15 P16050 2/20 0.37
HTR2A P28223 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CYP2D6 P10635 1/20 0.33
SRC P12931 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13388150 0.97 CYP2C19 (0.36) TSHRDPP4ALDH1A1CYP2C19F2
SCHEMBL7736448 0.82 PGK1 (0.40)
SCHEMBL7057745 0.81 LTA4H (0.46) TSHRSMN1; SMN2
SCHEMBL28845872 0.79 DPP4 (0.38) TSHRDPP4CYP2C19F2HTR2A
SCHEMBL7170910 0.78 TSHR (0.40) TSHRALDH1A1CYP2C19CYP3A4KDM4E
SCHEMBL4482935 0.77
SCHEMBL16924879 0.76 DPP4 (0.39) TSHRDPP4F2HTR2ATAAR1
SCHEMBL4853724 0.75 CHRNA7 (0.39) ALDH1A1MAPTSMN1; SMN2
SCHEMBL1435360 0.75
SCHEMBL9472870 0.75 ESR1 (0.44) TSHRALDH1A1CYP2C19CYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108126749-B Porous alkaline supported ionic liquid catalyst and preparation method and application thereof 中国科学院过程工程研究所 2020-10-02 CN claimed
US-8987520-B2 Fluoroalkyl and chlorofluoroalkyl benzenes E I DU PONT DE NEMOURS AND COMPANY (US) 2015-03-24 US claimed
CN-101787011-B Lateral difluoro methylene ether bridged bond double-terminal alkyl terphenyl liquid crystal compound and preparation method and application thereof UNIV TSINGHUA 2012-05-23 CN claimed
CN-101787011-A Side difluoro methylene ether bridged bond paired-end alkyl terphenyl liquid crystal compound, preparation method and application thereof UNIV TSINGHUA 2010-07-28 CN claimed
US-7405331-B2 High-purity (fluoroalkyl)benzene derivative and process for producing the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2008-07-29 US claimed
US-20060167324-A1 High-purity (fluoroalkyl)benzene derivative and process for producing the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2006-07-27 US claimed
EP-1500641-A1 HIGH-PURITY (FLUOROALKYL)BENZENE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2005-01-26 EP claimed
JP-6122636-A None JP disclosed
US-12384911-B2 Sulfur-containing polymers and methods of making the same ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2025-08-12 US disclosed
EP-3527593-B1 ISOCYANATE COMPOSITION, METHOD FOR PRODUCING ISOCYANATE COMPOSITION, AND METHOD FOR PRODUCING ISOCYANATE POLYMER ASAHI CHEMICAL IND (JP) 2025-07-23 EP disclosed
EP-3527600-B1 ISOCYANATE COMPOSITION AND PRODUCTION METHOD FOR ISOCYANATE POLYMER ASAHI CHEMICAL IND (JP) 2025-07-09 EP disclosed
US-20230194987-A1 PHOTORESIST POLYMER AND PHOTORESIST COMPOSITION INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-06-22 US disclosed
CN-114051502-B Phosphorus-containing resin terminated at end with unsaturated group, process for producing the same, and resin composition containing phosphorus-containing resin terminated at end with unsaturated group 可隆工业株式会社 2023-06-09 CN disclosed
CN-1165566-A Liquid crystal display element, method for manufacturing spacer frame thereof, and liquid crystal display element using spacer frame NATOCO PAINT KK (JP) 1997-11-19 CN disclosed
JP-H06122636-A 4-FLUOROALKYL BENZENE DERIVATIVE DAINIPPON INK & CHEM INC 1994-05-06 JP disclosed
EP-0106023-B1 END-CAPPED POLYARYLENE POLYETHERS, ARTICLES MADE THEREFROM AND PROCESS FOR PREPARING SUCH POLYARYLENE POLYETHERS AMOCO CORPORATION (US) 1988-03-30 EP disclosed
EP-0000503-A1 Polymer dispersions in polyols containing unsaturation THE DOW CHEMICAL COMPANY (US) 1979-02-07 EP disclosed
US-4098829-A POLYMERIC HYDROQUINONE ANTIOXIDANT DYNAPOL (US) 1978-07-04 US disclosed
US-4062862-A MUSCLE RELAXANT NIPPON CHEMIPHAR CO., LTD. (JA) 1977-12-13 US disclosed
US-4054676-A Edible with polymeric hydroquinone antioxidant DYNAPOL (US) 1977-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060167324-A1 High-purity (fluoroalkyl)benzene derivative and process for producing the same HBB, AFF4, AFF2 TSHR 1513/4885DPP4 2494/4885ALDH1A1 669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.