Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3949902 | 0.80 | DPP4 (0.38) | DPP4F2TSHRTAAR1LMNA | |
| SCHEMBL7793933 | 0.78 | CYP2D6 (0.37) | KMT2ADPP4F2TSHRTAAR1 | |
| SCHEMBL31028945 | 0.77 | MEN1 (0.41) | MEN1KMT2AATMDPP4F2 | |
| SCHEMBL8613849 | 0.75 | MEN1 (0.39) | MEN1KMT2AATMDPP4F2 | |
| SCHEMBL692130 | 0.75 | MEN1 (0.39) | MEN1KMT2AATMDPP4F2 | |
| SCHEMBL2398534 | 0.73 | MEN1 (0.38) | MEN1KMT2AATMDPP4F2 | |
| Methane SCHEMBL11662057 | 0.73 | MEN1 (0.38) | MEN1KMT2AATMDPP4F2 | |
| SCHEMBL5855141 | 0.73 | TRPA1 (0.45) | MEN1KMT2AATMDPP4F2 | |
| SCHEMBL2398537 | 0.73 | MEN1 (0.38) | MEN1KMT2AATMDPP4F2 | |
| SCHEMBL5855165 | 0.73 | TRPA1 (0.45) | MEN1KMT2AATMDPP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108707067-A | A kind of preparation method of three fluoro- 1- butanone compounds of 1- aryl -4,4,4- | 大连理工大学 | 2018-10-26 | — | — | CN | disclosed |
| CN-106588807-A | Olefin compound containing gem-difluoro-methylene and preparing method thereof | 上海大学 | 2017-04-26 | — | — | CN | disclosed |
| EP-0916640-B1 | 1,4-diaryl-2,3-difluoro-2-butene insecticidal and acaricidal agents | BASF AG (DE) | 2002-06-12 | — | — | EP | disclosed |
| US-3987087-A | ANTI-ULCER, NASAL PATENCY, WOUND HEALING, LABOR INDUCEMENT | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3983157-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1976-09-28 | — | — | US | disclosed |
| US-3983158-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1976-09-28 | — | — | US | disclosed |
| US-3980694-A | ANTIULCER, ANTIAGGLOMERANTS, INCREASE OF NASAL PATENCY, LABOR INDUCEMENT, WOUND HEALINGPROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1976-09-14 | — | — | US | disclosed |
| US-3931289-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1976-01-06 | — | — | US | disclosed |