Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CRHBP | P24387 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dioxane SCHEMBL305440 | 1.00 | — | — | |
| Dioxane SCHEMBL5000306 | 0.94 | — | — | |
| Oxirane SCHEMBL125747 | 0.93 | — | — | |
| Oxirane SCHEMBL2394418 | 0.93 | — | — | |
| Dioxane SCHEMBL9836999 | 0.93 | — | — | |
| Dioxane SCHEMBL3631647 | 0.93 | TTR (1.00) | TTRALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL6057268 | 0.93 | TTR (1.00) | TTRALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL78595 | 0.93 | TTR (1.00) | TTRALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL11207601 | 0.93 | TTR (1.00) | TTRALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL3137753 | 0.93 | TTR (1.00) | TTRALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107382894-A | A kind of preparation method of benzoxazole derivative | 浙江大学 | 2017-11-24 | — | — | CN | disclosed |
| CN-105272884-B | Method for preparing o-cyano benzophenone derivatives | 浙江大学 | 2017-05-24 | — | — | CN | disclosed |