⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dioxane SCHEMBL28845935 | 1.00 | TTR (0.86) | — | |
| Dioxane SCHEMBL5000306 | 0.94 | — | — | |
| Oxirane SCHEMBL125747 | 0.93 | — | — | |
| Oxirane SCHEMBL2394418 | 0.93 | — | — | |
| Dioxane SCHEMBL9836999 | 0.93 | — | — | |
| Dioxane SCHEMBL3631647 | 0.93 | TTR (1.00) | — | |
| SCHEMBL6057268 | 0.93 | TTR (1.00) | — | |
| SCHEMBL78595 | 0.93 | TTR (1.00) | — | |
| SCHEMBL11207601 | 0.93 | TTR (1.00) | — | |
| SCHEMBL3137753 | 0.93 | TTR (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108962-B | Method for continuously synthesizing azabicyclo compound | 上海巽田科技股份有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-117699808-A | Efficient heat-insulating light transparent silica aerogel material and preparation method thereof | 航天特种材料及工艺技术研究所 | 2024-03-15 | — | — | CN | claimed |
| CN-117430569-A | Synthesis method of 4, 6-dinitro-5, 7-diaminobenzofuroxan and 1,3, 5-triamino-2, 4, 6-trinitrobenzene | 中国工程物理研究院化工材料研究所 | 2024-01-23 | — | — | CN | claimed |
| CN-117024485-A | Synthesis method of 2' -OMe adenosine | 江苏申基生物科技有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-116120243-A | aPKC inhibitor compound intermediate fragment, preparation method and application thereof | 都创(上海)医药科技股份有限公司 | 2023-05-16 | — | — | CN | claimed |
| CN-112552233-A | Synthetic method of 2-amino-4-fluoropyridine | 镇江卡博医药科技有限公司 | 2021-03-26 | — | — | CN | claimed |
| CN-111777518-A | Synthetic preparation method of phenylethanolamine A labeled by stable isotope | 上海安谱实验科技股份有限公司 | 2020-10-16 | — | — | CN | claimed |
| CN-106928114-B | Cyclic chiral amino compound containing carbamido group and its amplifying process and use | 韶远科技（上海)有限公司 | 2020-07-28 | — | — | CN | claimed |
| CN-111187325-A | Anti-tumor (4' R) -methyl- α -L-ribofuranose nucleoside and preparation method thereof | 郑州大学 | 2020-05-22 | — | — | CN | claimed |
| CN-110606850-A | 3-benzo [4,5] imidazo [1,2-a ] pyrazine-1-amine compound and preparation method and application thereof | 中山大学 | 2019-12-24 | — | — | CN | claimed |
| CN-104370851-A | Synthesis method of 2-aminomethyl-thiazole hydrochloride | KEJIE BIO SUZHOU PHARMACEUTICALS CO LTD | 2015-02-25 | — | — | CN | claimed |
| CN-103788160-A | (2R,5R)-5-phosphoryl methoxy-2-(2-substituted adenine-9-yl)-2,5-dihydrofuran nucleoside analog as well as preparation method and application thereof | UNIV ZHENGZHOU | 2014-05-14 | — | — | CN | claimed |
| CN-103242304-A | Synthetic method of anti-inflammatory drug tenidap sodium | KEJIE BIO SUZHOU PHARMACEUTICAL CO LTD | 2013-08-14 | — | — | CN | claimed |
| WO-2013080215-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF FLUPIRTINE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | ARCH PHARMALABS LIMITED (IN) | 2013-06-06 | — | — | WO | claimed |
| CN-118119625-A | Pyrimidine-2 (1H) -keto bicyclic compounds with MAT2A inhibitory activity and application thereof | 上海海和药物研究开发股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-117858879-A | CDK2/4/6 inhibitor and preparation method and application thereof | 南京再明医药有限公司 | 2024-04-09 | — | — | CN | disclosed |
| US-11912721-B2 | Fused pentacyclic imidazole derivatives | UCB Biopharma SRL (BE) | 2024-02-27 | — | — | US | disclosed |
| US-4540524-A | Methods for preparing lower alkyl α-fluoro-α-cyanoacetate and its carbanion | DAIKIN KOGYO CO., LTD. (JP) | 1985-09-10 | — | — | US | disclosed |
| EP-0102086-A2 | Alpha-substituted-alpha-fluoro-alpha-cyanoacetic acid or its derivatives | Daikin Kogyo Co., Ltd. (JP) | 1984-03-07 | — | — | EP | disclosed |
| US-3989640-A | SYNERGISTIC, MORPHOLINE, AMMONIUM BENZOATE AND CYCLOHEXANE OR NITROPROPANE OR CYCLOPENTENE | THE DRACKETT COMPANY (US) | 1976-11-02 | — | — | US | disclosed |