Hydroxyl Radical

Hydroxyl Radical

SCHEMBL28845936

S=C1C=Cc2cccc3cccc1c23.[OH]

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.41
BCHE P06276 2/20 0.41
CES1 P23141 2/20 0.41
CES2 O00748 1/20 0.41
MCL1 Q07820 1/20 0.41
MAPK1 P28482 4/20 0.40
MAPT P10636 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HSD17B10 Q99714 5/20 0.39
TSHR P16473 3/20 0.39
ATM Q13315 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CASP1 P29466 2/20 0.36
CASP7 P55210 2/20 0.36
CYP3A4 P08684 2/20 0.36
PABPC1 P11940 2/20 0.36
DNMT1 P26358 2/20 0.36
HPGD P15428 4/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1081981 0.98 ALDH1A1 (0.43) ALDH1A1BCHECES1CES2MCL1
SCHEMBL28820242 0.96 ALDH1A1 (0.41) ALDH1A1BCHECES1CES2MCL1
Hydrogen Sulfide SCHEMBL28178887 0.96 ALDH1A1 (0.41) ALDH1A1BCHECES1CES2MCL1
Water SCHEMBL27288161 0.96 ALDH1A1 (0.41) ALDH1A1BCHECES1CES2MCL1
Formaldehyde SCHEMBL27291993 0.92 ALDH1A1 (0.43) ALDH1A1BCHECES1CES2MCL1
Sulfur Dioxide SCHEMBL21196862 0.90 ALDH1A1 (0.42) ALDH1A1BCHECES1CES2MCL1
Formaldehyde SCHEMBL28479013 0.90 ALDH1A1 (0.42) ALDH1A1BCHECES1CES2MCL1
Sulfur Dioxide SCHEMBL28093552 0.89 ALDH1A1 (0.41) ALDH1A1BCHECES1CES2MCL1
Thiosulfuric Acid SCHEMBL27898230 0.87 ALDH1A1 (0.39) ALDH1A1BCHECES1CES2MCL1
SCHEMBL28278114 0.87 ALDH1A1 (0.35) ALDH1A1BCHECES1CES2MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106928710-B Polyphenyl thioether composite material and preparation method thereof 苏州纳磐新材料科技有限公司 2019-05-07 CN disclosed
CN-106928710-A Polyphenyl thioether composite material and preparation method thereof 苏州纳磐新材料科技有限公司 2017-07-07 CN disclosed