Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Sulfur Dioxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 2/20 | 0.40 |
| ▸ | TYMS known ✓ | P04818 | 4/20 | 0.34 |
| ▸ | PARP1 known ✓ | P09874 | 1/20 | 0.33 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.33 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfur Dioxide SCHEMBL21196862 | 0.98 | ALDH1A1 (0.42) | ALDH1A1BCHECES1CES2MCL1 | |
| Water SCHEMBL27288161 | 0.93 | ALDH1A1 (0.41) | ALDH1A1BCHECES1CES2MCL1 | |
| Formaldehyde SCHEMBL28479013 | 0.91 | ALDH1A1 (0.42) | ALDH1A1BCHECES1CES2MCL1 | |
| SCHEMBL1081981 | 0.91 | ALDH1A1 (0.43) | ALDH1A1BCHECES1CES2MCL1 | |
| Formaldehyde SCHEMBL27291993 | 0.89 | ALDH1A1 (0.43) | ALDH1A1BCHECES1CES2MCL1 | |
| Hydrogen Sulfide SCHEMBL28178887 | 0.89 | ALDH1A1 (0.41) | ALDH1A1BCHECES1CES2MCL1 | |
| SCHEMBL28820242 | 0.89 | ALDH1A1 (0.41) | ALDH1A1BCHECES1CES2MCL1 | |
| Hydroxyl Radical SCHEMBL28845936 | 0.89 | ALDH1A1 (0.41) | ALDH1A1BCHECES1CES2MCL1 | |
| Thiosulfuric Acid SCHEMBL27898230 | 0.84 | ALDH1A1 (0.39) | ALDH1A1BCHECES1CES2MCL1 | |
| Water SCHEMBL28305616 | 0.83 | ALDH1A1 (0.36) | ALDH1A1BCHECES1CES2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151989-A | Film for thin film capacitor, metal layer laminated film for thin film capacitor, and thin film capacitor | 东丽株式会社 | 2022-10-04 | — | — | CN | disclosed |
| CN-112533977-A | Crystalline wholly aromatic polyester and polyester resin composition | 引能仕株式会社 | 2021-03-19 | — | — | CN | disclosed |
| CN-110016206-A | A kind of resin combination, the prepreg comprising it and laminate and printed circuit board | 广东生益科技股份有限公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-109312091-A | High internal phase emulsion foam with cellulose nano particle | 宝洁公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-109197805-A | Fishing tackle component and force-releasing device of fishing tackle fishing reel using same | 帝人株式会社 | 2019-01-15 | — | — | CN | disclosed |
| CN-108779585-A | Yarn and cloth and silk and fibre | 帝人富瑞特株式会社 | 2018-11-09 | — | — | CN | disclosed |
| CN-106029784-B | Resin combination | 帝人株式会社 | 2018-09-18 | — | — | CN | disclosed |
| CN-107206299-A | Filter cloth for bag filter, method for manufacturing same, and bag filter | 帝人株式会社 | 2017-09-26 | — | — | CN | disclosed |
| CN-106334461-A | PVDF and PSF binary blended ultrafiltration membrane and preparation method thereof | 天津华清健坤膜科技有限公司 | 2017-01-18 | — | — | CN | disclosed |
| CN-103118771-B | Film laminated permeable membrane | 新加坡国立大学 | 2016-11-09 | — | — | CN | disclosed |
| CN-106029784-A | Resin composition | 帝人株式会社 | 2016-10-12 | — | — | CN | disclosed |
| CN-105829411-A | Ion exchange membranes made from biaxially stretched beta-porous films | 特里奥凡德国有限公司及两合公司 | 2016-08-03 | — | — | CN | disclosed |