Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 6/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAK | O14976 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.32 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2876029 | 0.79 | CYP1A1 (0.48) | CYP1A1CYP1A2CYP1B1APPGRM5 | |
| SCHEMBL2890272 | 0.79 | CYP2D6 (0.37) | TSHRPTPN11CYP1A2APPEGFR | |
| SCHEMBL21034366 | 0.79 | PTPN11 (0.37) | PTPN11CYP1A1CYP1A2CYP1B1EGFR | |
| SCHEMBL2892134 | 0.79 | TSHR (0.37) | TSHRPTPN11CYP1A2APPEGFR | |
| SCHEMBL9460886 | 0.79 | TSHR (0.37) | TSHRPTPN11APPEGFRGRM5 | |
| SCHEMBL2892638 | 0.79 | HRH3 (0.44) | TSHRPTPN11APPEGFRGRM5 | |
| SCHEMBL10191908 | 0.77 | ALDH1A1 (0.45) | PTPN11CYP1A1CYP1A2CYP1B1EGFR | |
| SCHEMBL10191916 | 0.77 | KCNA5 (0.44) | PTPN11CYP1A1CYP1A2CYP1B1EGFR | |
| SCHEMBL2892636 | 0.77 | EGFR (0.43) | TSHREGFRALDH1A1MAPTGAK | |
| SCHEMBL361389 | 0.77 | MAPT (0.53) | ALDH1A1MAPTABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | FUJIFILM CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
| EP-2202220-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | KAT8, HDAC10, SSRP1 | TSHR 4692/4885PTPN11 4656/4885CYP1A1 2489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.