SCHEMBL21034366

SCHEMBL21034366

CC#Cc1cccc(NSF)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 1/20 0.37
CYP1A1 P04798 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP1B1 Q16678 2/20 0.36
EGFR P00533 4/20 0.33
TAS2R14 Q9NYV8 1/20 0.33
IKBKB O14920 2/20 0.32
GRM5 P41594 1/20 0.31
PDK1 Q15118 1/20 0.31
PDK2 Q15119 1/20 0.31
PDK3 Q15120 1/20 0.31
PDK4 Q16654 1/20 0.31
HAO1 Q9UJM8 1/20 0.31
SYK P43405 1/20 0.31
GFER P55789 1/20 0.30
ALDH1A1 P00352 2/20 0.30
MAPT P10636 2/20 0.30
GAK O14976 1/20 0.30
FBP1 P09467 1/20 0.30
ABCG2 Q9UNQ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2884609 0.79 TSHR (0.41) PTPN11CYP1A1CYP1A2CYP1B1EGFR
SCHEMBL2876029 0.75 CYP1A1 (0.48) CYP1A1CYP1A2CYP1B1GRM5HAO1
SCHEMBL10191916 0.73 KCNA5 (0.44) PTPN11CYP1A1CYP1A2CYP1B1EGFR
SCHEMBL10191908 0.73 ALDH1A1 (0.45) PTPN11CYP1A1CYP1A2CYP1B1EGFR
SCHEMBL10191902 0.71 ALDH1A1 (0.59) PTPN11CYP1A2EGFRIKBKBGRM5
SCHEMBL22658427 0.71 PTPN11 (0.57) PTPN11IKBKBGRM5PDK1PDK2
SCHEMBL10191897 0.71 IKBKB (0.52) CYP1A2IKBKBALDH1A1MAPT
SCHEMBL14515380 0.70 L3MBTL1 (0.60) PTPN11CYP1A2IKBKBPDK1PDK2
SCHEMBL935880 0.70 CA12 (0.50) CYP1A1CYP1A2CYP1B1IKBKBGRM5
SCHEMBL23549950 0.69 CYP1A1 (0.38) CYP1A1CYP1A2CYP1B1TAS2R14GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019101132-A1 FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF 中国科学院上海有机化学研究所 2019-05-31 WO disclosed