Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9485267 | 0.80 | LMNA (0.64) | SMN1; SMN2CYP1A2MEN1LMNATP53 | |
| SCHEMBL9893083 | 0.79 | NPC1 (0.47) | SMN1; SMN2CYP1A2MEN1KMT2APSMB8 | |
| Albendazole SCHEMBL29409236 | 0.78 | LMNA (0.83) | SMN1; SMN2CYP1A2MEN1LMNATP53 | |
| Albendazole SCHEMBL7969988 | 0.78 | LMNA (0.83) | SMN1; SMN2CYP1A2MEN1LMNATP53 | |
| Albendazole SCHEMBL44682 | 0.78 | LMNA (0.83) | SMN1; SMN2CYP1A2MEN1LMNATP53 | |
| SCHEMBL23894242 | 0.77 | LMNA (0.60) | SMN1; SMN2CYP1A2MEN1LMNATP53 | |
| SCHEMBL28846142 | 0.77 | LMNA (0.60) | SMN1; SMN2CYP1A2MEN1LMNATP53 | |
| Albendazole SCHEMBL28582887 | 0.77 | LMNA (0.81) | SMN1; SMN2CYP1A2MEN1LMNATP53 | |
| Albendazole SCHEMBL28958723 | 0.77 | LMNA (0.81) | SMN1; SMN2CYP1A2MEN1LMNATP53 | |
| SCHEMBL16254959 | 0.76 | NPC1 (0.49) | SMN1; SMN2CYP1A2MEN1KMT2APSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073380-A | 2-amide substituted benzo five-membered nitrogen-containing heterocyclic compound and preparation method and application thereof | 青海大学 | 2022-09-20 | — | — | CN | disclosed |