SCHEMBL28846366

SCHEMBL28846366

CCCCC(CCCC)CC(CCCC)(C(=O)O)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.39
MAPK1 P28482 1/20 0.39
ALDH1A1 P00352 2/20 0.38
TSHR P16473 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
CYP3A4 P08684 1/20 0.36
ATM Q13315 1/20 0.36
GPR84 Q9NQS5 3/20 0.34
CA1 P00915 1/20 0.34
FFAR1 O14842 1/20 0.34
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34
SLC1A1 P43005 1/20 0.34
HSPD1 P10809 1/20 0.33
BLM P54132 1/20 0.33
HSPE1 P61604 1/20 0.33
MAPT P10636 1/20 0.33
LMNA P02545 1/20 0.33
LCK P06239 1/20 0.33
PPARD Q03181 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28315889 0.84 GPR84 (0.43) GPR84FFAR1HSPD1BLMHSPE1
SCHEMBL453703 0.82 CA2 (0.48) CA2MAPK1ALDH1A1TSHRTDP1
SCHEMBL6158271 0.80 AKR1B1 (0.33) CA2MAPK1ALDH1A1TSHRGPR84
SCHEMBL476932 0.79 AKR1B1 (0.42) ALDH1A1TSHRTDP1GPR84FFAR1
SCHEMBL17106101 0.78 CA2 (0.50) CA2MAPK1TDP1GPR84CA1
SCHEMBL11587612 0.78 CA2 (0.44) CA2MAPK1ALDH1A1TSHRTDP1
SCHEMBL21269781 0.77 AKR1B1 (0.40) ALDH1A1TSHRTDP1GPR84FFAR1
Lithium SCHEMBL29455930 0.77 AKR1B1 (0.40) ALDH1A1TSHRTDP1GPR84FFAR1
SCHEMBL21270014 0.77 AKR1B1 (0.40) ALDH1A1TSHRTDP1GPR84FFAR1
SCHEMBL21270036 0.77 AKR1B1 (0.40) ALDH1A1TSHRTDP1GPR84FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106748724-A A kind of method for preparing Guerbet acid as raw material with malonate 中国科学院上海高等研究院 2017-05-31 CN disclosed