SCHEMBL2884712

SCHEMBL2884712

O=C1c2ccccc2C(=O)N1CCCCCl

nearest known ligand 0.61

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
MAPT P10636 1/20 0.61
RAB9A P51151 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
GLS O94925 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6786134 0.98 TDP1 (0.64) TDP1L3MBTL1MAPTRAB9ASMN1; SMN2
SCHEMBL30632351 0.98 TDP1 (0.64) TDP1L3MBTL1MAPTRAB9ASMN1; SMN2
SCHEMBL9536378 0.98 TDP1 (0.64) TDP1L3MBTL1MAPTRAB9ASMN1; SMN2
SCHEMBL31622484 0.94 MAPT (0.62) TDP1L3MBTL1MAPTRAB9ASMN1; SMN2
SCHEMBL5312972 0.94 MAPT (0.62) TDP1L3MBTL1MAPTRAB9ASMN1; SMN2
SCHEMBL6790333 0.89 TDP1 (0.71) TDP1L3MBTL1MAPTRAB9ASMN1; SMN2
SCHEMBL8862878 0.87 TDP1 (0.75) TDP1L3MBTL1
SCHEMBL2604742 0.87 TDP1 (0.75) TDP1L3MBTL1
SCHEMBL8862728 0.87 TDP1 (0.75) TDP1L3MBTL1
SCHEMBL6777483 0.87 TDP1 (0.75) TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1660560-B1 PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-03-23 EP claimed
US-7714095-B2 Phase transfer catalyzed method for preparation of polyetherimides SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-05-11 US claimed
JP-2009521548-A 2009-06-04 JP claimed
CN-101374908-A Foamed and foamable high glass transition temperature polymers GEN ELECTRIC (US) 2009-02-25 CN claimed
CN-101370873-A Annular or tubular shaped articles of novel polymer blends GEN ELECTRIC (US) 2009-02-18 CN claimed
CN-101370872-A Food service articles of manufacture comprising high temperature polymers GEN ELECTRIC (US) 2009-02-18 CN claimed
CN-101351506-A High glass transition temperature thermoplastic articles GEN ELECTRIC (US) 2009-01-21 CN claimed
EP-1989246-A2 PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETHERIMIDES Sabic Innovative Plastics IP B.V. (NL) 2008-11-12 EP claimed
EP-1966320-A2 HIGH GLASS TRANSITION TEMPERATURE THERMOPLASTIC ARTICLES General Electric Company (US) 2008-09-10 EP claimed
EP-1963433-A2 ANNULAR OR TUBULAR SHAPED ARTICLES OF NOVEL POLYMER BLENDS General Electric Company (US) 2008-09-03 EP claimed
US-20070065615-A1 ANNULAR OR TUBULAR SHAPED ARTICLES OF NOVEL POLYMER BLENDS CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-22 US claimed
CN-1871280-A Phase transfer catalytic process for the preparation of polyetherimides GEN ELECTRIC (US) 2006-11-29 CN claimed
CN-1867610-A Copolyetherimides GEN ELECTRIC (US) 2006-11-22 CN claimed
US-20060173158-A1 Phase transfer catalyzed method for preparation of polyetherimides GENERAL ELECTRIC COMPANY (US) 2006-08-03 US claimed
EP-1660560-A2 PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES GENERAL ELECTRIC COMPANY (US) 2006-05-31 EP claimed
EP-1660556-A1 COPOLYETHERIMIDES GENERAL ELECTRIC COMPANY (US) 2006-05-31 EP claimed
WO-2005023901-A1 COPOLYETHERIMIDES GENERAL ELECTRIC COMPANY (US) 2005-03-17 WO claimed
WO-2005021618-A2 PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES GENERAL ELECTRIC COMPANY (US) 2005-03-10 WO claimed
US-20050049390-A1 Phase transfer catalyzed method for preparation of polyetherimides GENERAL ELECTRIC COMPANY 2005-03-03 US claimed
US-6849706-B1 Copolyetherimides GENERAL ELECTRIC COMPANY (US) 2005-02-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060173158-A1 Phase transfer catalyzed method for preparation of polyetherimides TRRAP, RCC1, DDT TDP1 2106/4885L3MBTL1 1690/4885MAPT 1031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.