SCHEMBL2884714

SCHEMBL2884714

CCCCN1C(=O)c2ccc(Cl)cc2C1=O

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 7/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
MAPK1 P28482 4/20 0.46
LMNA P02545 2/20 0.46
CHRM2 P08172 1/20 0.46
TSHR P16473 1/20 0.45
HTT P42858 1/20 0.45
TP53 P04637 1/20 0.45
MAPT P10636 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
HTR1A P08908 1/20 0.45
DRD2 P14416 1/20 0.45
HTR2A P28223 1/20 0.45
USP2 O75604 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10451411 0.94 CNR2 (0.50)
SCHEMBL2892202 0.94 CNR2 (0.50)
SCHEMBL10779928 0.90 KDM4E (0.46) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL9375873 0.83 KDM4E (0.49) KDM4EALDH1A1MEN1KMT2AMAPK1
SCHEMBL8502643 0.83 KDM4E (0.70) KDM4EALDH1A1MEN1KMT2AMAPK1
SCHEMBL17946339 0.83 KDM4E (0.70) KDM4EALDH1A1MEN1KMT2AMAPK1
SCHEMBL14560531 0.82 CA1 (0.45) KDM4EALDH1A1MEN1KMT2AMAPK1
SCHEMBL10451194 0.82 POLB (0.57) KDM4EALDH1A1MEN1KMT2ALMNA
SCHEMBL9383842 0.82 ALDH1A1 (0.48) KDM4EALDH1A1KMT2AMAPK1TSHR
SCHEMBL14338933 0.81 CHRM2 (0.66) KDM4EALDH1A1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1660560-B1 PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-03-23 EP claimed
US-7714095-B2 Phase transfer catalyzed method for preparation of polyetherimides SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-05-11 US claimed
CN-101463132-A Polythioether acid imide and preparation thereof NINGBO INST MAT TECH & ENG CAS (CN) 2009-06-24 CN claimed
JP-2009521548-A 2009-06-04 JP claimed
CN-101374908-A Foamed and foamable high glass transition temperature polymers GEN ELECTRIC (US) 2009-02-25 CN claimed
CN-101370873-A Annular or tubular shaped articles of novel polymer blends GEN ELECTRIC (US) 2009-02-18 CN claimed
CN-101370872-A Food service articles of manufacture comprising high temperature polymers GEN ELECTRIC (US) 2009-02-18 CN claimed
CN-101351506-A High glass transition temperature thermoplastic articles GEN ELECTRIC (US) 2009-01-21 CN claimed
EP-1989246-A2 PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETHERIMIDES Sabic Innovative Plastics IP B.V. (NL) 2008-11-12 EP claimed
EP-1966320-A2 HIGH GLASS TRANSITION TEMPERATURE THERMOPLASTIC ARTICLES General Electric Company (US) 2008-09-10 EP claimed
CN-1871280-A Phase transfer catalytic process for the preparation of polyetherimides GEN ELECTRIC (US) 2006-11-29 CN claimed
CN-1867610-A Copolyetherimides GEN ELECTRIC (US) 2006-11-22 CN claimed
US-20060173158-A1 Phase transfer catalyzed method for preparation of polyetherimides GENERAL ELECTRIC COMPANY (US) 2006-08-03 US claimed
EP-1660556-A1 COPOLYETHERIMIDES GENERAL ELECTRIC COMPANY (US) 2006-05-31 EP claimed
EP-1660560-A2 PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES GENERAL ELECTRIC COMPANY (US) 2006-05-31 EP claimed
WO-2005023901-A1 COPOLYETHERIMIDES GENERAL ELECTRIC COMPANY (US) 2005-03-17 WO claimed
WO-2005021618-A2 PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES GENERAL ELECTRIC COMPANY (US) 2005-03-10 WO claimed
US-20050049390-A1 Phase transfer catalyzed method for preparation of polyetherimides GENERAL ELECTRIC COMPANY 2005-03-03 US claimed
US-6849706-B1 Copolyetherimides GENERAL ELECTRIC COMPANY (US) 2005-02-01 US claimed
US-4730055-A Method for silylating aromatic imides and silylimides made therefrom GENERAL ELECTRIC COMPANY (US) 1988-03-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060173158-A1 Phase transfer catalyzed method for preparation of polyetherimides TRRAP, RCC1, DDT KDM4E 1288/4885ALDH1A1 3919/4885MEN1 4568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.