Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.32 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.32 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.32 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.32 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28133636 | 0.87 | GRIK1 (0.46) | GPR52FFAR1GRIK1 | |
| SCHEMBL28159928 | 0.86 | GRIK1 (0.37) | GRIK1 | |
| SCHEMBL28129210 | 0.82 | FFAR1 (0.44) | GPR52FFAR1FFAR4POLBTAAR1 | |
| SCHEMBL28168829 | 0.82 | GPR52 (0.32) | GPR52 | |
| SCHEMBL28159931 | 0.78 | GPR52 (0.47) | GPR52FFAR1FFAR4TAAR1 | |
| SCHEMBL28160455 | 0.74 | AKR1C3 (0.39) | POLBCTDSP1 | |
| SCHEMBL28849286 | 0.74 | TDP1 (0.33) | GPR52POLB | |
| SCHEMBL28169295 | 0.74 | FFAR4 (0.36) | GPR52FFAR4POLB | |
| SCHEMBL441351 | 0.73 | GPR52 (0.50) | GPR52FFAR1FFAR4PDPK1PPARD | |
| SCHEMBL1919934 | 0.73 | GPR52 (0.50) | GPR52FFAR1FFAR4PDPK1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104860867-B | The dione compounds of 2,3 2 substitution 1H benzo [f] indoles 4,9 and its preparation method | 浙江大学 | 2017-06-13 | — | — | CN | disclosed |