Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28169295 | 0.90 | FFAR4 (0.36) | TDP1SRCKMT2APOLBL3MBTL1 | |
| SCHEMBL28159931 | 0.82 | GPR52 (0.47) | KMT2AKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL28168829 | 0.81 | GPR52 (0.32) | GPR52 | |
| SCHEMBL23148058 | 0.76 | SLC9A3 (0.36) | TDP1SRCKMT2APOLBL3MBTL1 | |
| SCHEMBL28849269 | 0.75 | TAS2R14 (0.36) | MAPT | |
| SCHEMBL28847179 | 0.74 | GPR52 (0.43) | POLBGPR52 | |
| SCHEMBL28133636 | 0.72 | GRIK1 (0.46) | SMN1; SMN2ALDH1A1GPR52 | |
| SCHEMBL28169406 | 0.71 | POLQ (0.40) | — | |
| SCHEMBL28169317 | 0.71 | POLQ (0.41) | KDM4EALDH1A1LMNARAB9A | |
| SCHEMBL28159928 | 0.69 | GRIK1 (0.37) | KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107098846-A | N- acyl sulfonamides class FBPase inhibitor, its preparation method, pharmaceutical composition and purposes | 中国医学科学院药物研究所 | 2017-08-29 | — | — | CN | disclosed |