Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947157 | 1.00 | TDP1 (0.50) | TDP1TSHRMAPK1MAPTLMNA | |
| SCHEMBL11462352 | 0.88 | TSHR (0.51) | TDP1TSHRMAPTLMNAALDH1A1 | |
| SCHEMBL28847407 | 0.83 | APP (0.51) | TDP1TSHRMAPK1MAPTLMNA | |
| SCHEMBL29947126 | 0.83 | APP (0.51) | TDP1TSHRMAPK1MAPTLMNA | |
| SCHEMBL6296295 | 0.82 | TDP1 (0.58) | TDP1TSHRMAPK1MAPTLMNA | |
| SCHEMBL27764339 | 0.81 | MAPT (0.48) | TDP1TSHRMAPK1MAPTLMNA | |
| SCHEMBL11460934 | 0.80 | VCAM1 (0.51) | MAPK1MAPTLMNAALDH1A1APP | |
| SCHEMBL9727361 | 0.80 | AR (0.55) | TSHRMAPK1LMNAALDH1A1SIRT6 | |
| SCHEMBL15451317 | 0.78 | EPHX1 (0.50) | TDP1TSHRMAPTALDH1A1EPHX1 | |
| SCHEMBL31480794 | 0.78 | ALDH1A1 (0.51) | TDP1TSHRMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087655-A | Benzimidazole derivatives | 辉瑞公司 | 2022-09-20 | — | — | CN | disclosed |