Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | RAC1 | P63000 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28847447 | 0.88 | MAPT (0.43) | MAPTALDH1A1KDM4EGAAPKM | |
| SCHEMBL28847456 | 0.86 | NPC1 (0.46) | MAPTALDH1A1KDM4EGAAPKM | |
| SCHEMBL28847416 | 0.79 | HTT (0.41) | MAPTALDH1A1GAANPC1RAB9A | |
| SCHEMBL28847499 | 0.78 | ALDH1A1 (0.37) | MAPTALDH1A1KDM4EGAAPKM | |
| SCHEMBL28847454 | 0.77 | ALDH1A1 (0.38) | MAPTALDH1A1KDM4EGAANPC1 | |
| SCHEMBL28847473 | 0.77 | AAK1 (0.41) | MAPTALDH1A1NPC1RAB9ACYP3A4 | |
| SCHEMBL28847474 | 0.76 | ALDH1A1 (0.36) | MAPTALDH1A1KDM4EGAANPC1 | |
| SCHEMBL28847511 | 0.75 | RAC1 (0.39) | MAPTALDH1A1KDM4EGAAPKM | |
| SCHEMBL29947126 | 0.74 | APP (0.51) | MAPTALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28847407 | 0.74 | APP (0.51) | MAPTALDH1A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087655-A | Benzimidazole derivatives | 辉瑞公司 | 2022-09-20 | — | — | CN | disclosed |