Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28847454 | 0.81 | ALDH1A1 (0.38) | HTTKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL28847442 | 0.80 | KDM1A (0.41) | HTTKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL28847449 | 0.79 | MAPT (0.41) | HTTALDH1A1MAPTGAANPC1 | |
| SCHEMBL28847474 | 0.79 | ALDH1A1 (0.36) | HTTKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL28847386 | 0.78 | HTT (0.41) | HTTKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL23524981 | 0.75 | AAK1 (0.47) | HTTKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL23524984 | 0.75 | AAK1 (0.47) | HTTKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL28847388 | 0.74 | MAPT (0.41) | KMT2AALDH1A1MAPTMEN1L3MBTL1 | |
| SCHEMBL23525075 | 0.74 | ITK (0.41) | HTTKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL23525077 | 0.74 | ITK (0.41) | HTTKMT2AALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087655-A | Benzimidazole derivatives | 辉瑞公司 | 2022-09-20 | — | — | CN | disclosed |