Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947222 | 1.00 | MAPT (0.43) | MAPTTSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL28847462 | 0.80 | CD44 (0.35) | MAPTTSHRCYP3A4CYP1A2TDP1 | |
| SCHEMBL5953091 | 0.76 | TSHR (0.49) | MAPTTSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL348272 | 0.74 | TSHR (0.59) | MAPTTSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL11462352 | 0.74 | TSHR (0.51) | MAPTTSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL6405853 | 0.74 | ALDH1A1 (0.51) | MAPTTSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL29947157 | 0.74 | TDP1 (0.50) | MAPTTSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL28847439 | 0.74 | TDP1 (0.50) | MAPTTSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL10488867 | 0.73 | TSHR (0.57) | MAPTTSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL7461987 | 0.73 | TSHR (0.57) | MAPTTSHRALDH1A1CYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087655-A | Benzimidazole derivatives | 辉瑞公司 | 2022-09-20 | — | — | CN | disclosed |