Ethyl Pyruvate

Ethyl Pyruvate

SCHEMBL28847880

CCC(CO)(CO)CO.CCOC(=O)C(C)=O

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 1/20 0.45
ALDH1A1 P00352 6/20 0.41
LMNA P02545 1/20 0.41
HSD17B10 Q99714 1/20 0.41
PKM P14618 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MAPT P10636 2/20 0.37
NPSR1 Q6W5P4 1/20 0.36
TSHR P16473 1/20 0.35
CYP4F2 P78329 2/20 0.35
CYP4A11 Q02928 2/20 0.35
ALOX15 P16050 1/20 0.34
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
SOAT1 P35610 1/20 0.34
EGLN1 Q9GZT9 1/20 0.34
CYP2D6 P10635 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Acetate SCHEMBL17840978 0.83 ALDH1A1 (0.64) GLO1ALDH1A1LMNAHSD17B10PKM
Ethyl Pyruvate SCHEMBL25538 0.82
Ethyl Pyruvate SCHEMBL28156490 0.82 GLO1 (0.61) GLO1ALDH1A1LMNAHSD17B10MAPT
Ethyl Pyruvate SCHEMBL1331224 0.82
SCHEMBL10455203 0.80 ALDH1A1 (0.41) GLO1ALDH1A1LMNAHSD17B10PKM
Ethyl Pyruvate SCHEMBL28039252 0.79 GLO1 (0.58) GLO1ALDH1A1LMNAHSD17B10MAPT
Ethyl Pyruvate SCHEMBL27732737 0.79
Ethyl Pyruvate SCHEMBL30913010 0.79
Ethyl Pyruvate SCHEMBL27450365 0.79
Ethyl Pyruvate SCHEMBL27622493 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107075094-A High recycle content polyester polyols from hydroxy-functional ketal acids, esters or amides 树脂酸盐材料集团有限公司 2017-08-18 CN disclosed