Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31075519 | 0.98 | HDAC1 (0.51) | HDAC1ALDH1A1FAAHKMT2AGAA | |
| SCHEMBL24451230 | 0.93 | ALDH1A1 (0.55) | HDAC1ALDH1A1FAAHKMT2AGAA | |
| SCHEMBL28848245 | 0.84 | MAPT (0.52) | HDAC1ALDH1A1KMT2AGAASMN1; SMN2 | |
| SCHEMBL28674194 | 0.82 | FAAH (0.50) | HDAC1FAAHKMT2AGAASMN1; SMN2 | |
| SCHEMBL3231788 | 0.81 | HDAC1 (0.55) | HDAC1ALDH1A1FAAHKMT2ASMN1; SMN2 | |
| SCHEMBL6719477 | 0.81 | MAPT (0.50) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL28612298 | 0.81 | HDAC1 (0.51) | HDAC1ALDH1A1GAASMN1; SMN2LMNA | |
| SCHEMBL27713410 | 0.81 | GAA (0.40) | HDAC1ALDH1A1KMT2AGAASMN1; SMN2 | |
| SCHEMBL38659947 | 0.81 | TEK (0.47) | HDAC1FAAH | |
| SCHEMBL28668151 | 0.81 | FAAH (0.52) | HDAC1FAAHKMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957127-B | Glutamine acyl cyclase inhibitor and preparation method and application thereof | 深圳大学 | 2023-08-15 | — | — | CN | disclosed |
| CN-114957127-A | Glutaminyl cyclase inhibitor and preparation method and application thereof | 深圳大学 | 2022-08-30 | — | — | CN | disclosed |