Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3520084 | 0.90 | MAPK1 (0.47) | KDM4EMAPK1L3MBTL1KDM6BKDM5C | |
| SCHEMBL15712178 | 0.84 | MAPK1 (0.39) | KDM4EMAPK1L3MBTL1ALDH1A1ABL1 | |
| SCHEMBL15391826 | 0.83 | CYP2C9 (0.56) | KDM4EMAPK1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL3517645 | 0.82 | HCAR2 (0.48) | KDM4EHCAR2NAPRTALDH1A1CYP2C9 | |
| SCHEMBL473981 | 0.81 | OPRK1 (0.48) | KDM4EL3MBTL1ALDH1A1ABL1GAA | |
| SCHEMBL30816026 | 0.81 | OPRK1 (0.48) | KDM4EL3MBTL1ALDH1A1ABL1GAA | |
| SCHEMBL31069006 | 0.80 | KDM4E (0.46) | KDM4EMAPK1L3MBTL1KDM6BKDM5C | |
| SCHEMBL26101991 | 0.80 | KDM4E (0.46) | KDM4EMAPK1L3MBTL1KDM6BKDM5C | |
| SCHEMBL31368194 | 0.79 | CA12 (0.49) | KDM4EALDH1A1ABL1GAAHSD17B10 | |
| SCHEMBL26660324 | 0.79 | CA12 (0.49) | KDM4EALDH1A1ABL1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612158-B | The somatostatin receptor hypotype 5 (SSTR5) antagonist | 武田药品工业株式会社 | 2017-06-30 | — | — | CN | disclosed |