Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26101991 | 1.00 | KDM4E (0.46) | KDM4EMAPK1L3MBTL1KDM6BKDM5C | |
| SCHEMBL6237650 | 0.88 | POLB (0.43) | KDM4EMAPK1L3MBTL1ALDH1A1CYP2C9 | |
| SCHEMBL18584731 | 0.84 | HPGDS (0.43) | KDM4EMAPK1L3MBTL1ALDH1A1HCAR3 | |
| SCHEMBL26102920 | 0.81 | ATR (0.39) | KDM4EMAPK1L3MBTL1ALDH1A1GAA | |
| SCHEMBL30647070 | 0.80 | HPGDS (0.46) | KDM4EL3MBTL1CYP2C9CYP2C19HCAR3 | |
| SCHEMBL18584821 | 0.80 | HPGDS (0.46) | KDM4EL3MBTL1CYP2C9CYP2C19HCAR3 | |
| SCHEMBL30389862 | 0.80 | KDM4E (0.36) | KDM4EMAPK1L3MBTL1ALDH1A1GAA | |
| SCHEMBL28848352 | 0.80 | KDM4E (0.46) | KDM4EMAPK1L3MBTL1KDM6BKDM5C | |
| SCHEMBL22959274 | 0.79 | CA12 (0.49) | KDM4EALDH1A1GAAGLACYP2C9 | |
| SCHEMBL5781494 | 0.79 | ATM (0.47) | KDM4EALDH1A1GAAGLAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118510758-A | RXFP1 agonists | 百时美施贵宝公司 | 2024-08-16 | — | — | CN | disclosed |