Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 19/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | MAP3K6 | O95382 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28848874 | 0.88 | GSK3B (0.41) | MAP3K5GSK3BDYRK1A | |
| SCHEMBL28848835 | 0.77 | MAP3K5 (0.45) | MAP3K5MAP3K6 | |
| SCHEMBL25619965 | 0.74 | MAP3K5 (0.52) | MAP3K5 | |
| SCHEMBL25619955 | 0.73 | MAP3K5 (0.43) | MAP3K5 | |
| SCHEMBL29949178 | 0.73 | MAP3K5 (0.43) | MAP3K5 | |
| SCHEMBL28848716 | 0.73 | MAP3K5 (0.43) | MAP3K5MAP3K6 | |
| SCHEMBL12225872 | 0.73 | GSK3B (0.48) | GSK3BDYRK1A | |
| SCHEMBL15263847 | 0.72 | TGFBR1 (0.42) | GSK3BDYRK1A | |
| SCHEMBL16692819 | 0.71 | PSEN1 (0.44) | GSK3BDYRK1A | |
| SCHEMBL28848720 | 0.71 | MAP3K5 (0.42) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110036005-B | Amide derivatives and their use in medicine | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |