Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 15/20 | 0.38 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28848869 | 0.83 | MAP3K5 (0.38) | MAP3K5 | |
| SCHEMBL28848714 | 0.77 | MAP3K5 (0.42) | MAP3K5GRM5 | |
| SCHEMBL28848720 | 0.71 | MAP3K5 (0.42) | MAP3K5NOS3NOS1NOS2 | |
| SCHEMBL28848739 | 0.71 | MAP3K5 (0.38) | MAP3K5NR2E1GRM5 | |
| SCHEMBL21887465 | 0.71 | MAP3K5 (0.47) | MAP3K5 | |
| SCHEMBL29949305 | 0.71 | MAP3K5 (0.38) | MAP3K5NR2E1GRM5 | |
| SCHEMBL29404609 | 0.71 | MAP3K5 (0.47) | MAP3K5 | |
| SCHEMBL28927033 | 0.70 | MAP3K5 (0.41) | MAP3K5 | |
| SCHEMBL3783299 | 0.69 | NR2E1 (0.63) | MAP3K5NR2E1 | |
| SCHEMBL28848862 | 0.69 | MAP3K5 (0.38) | MAP3K5GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110036005-B | Amide derivatives and their use in medicine | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |